Pegaptanib

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

S01LA03

CAS registry number (Chemical Abstracts Service)

0222716-86-1

Chemical Formula

C294-H370-F13-N107-O188-P28[C2-H4-O]n

Therapeutic Categories

Ophthalmic agent for treatment of neovascular (wet) age-related macular degeneration

Angiogenesis inhibitor

Vascular Endothelial Growth Factor (VEGF) antagonist

Chemical Name

5'-Ester of (2'-deoxy-2'-fluoro)C-Gm-Gm-A-A-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-Am-Gm-(2'-deoxy-2'-fluoro)U-Gm-Am-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2'-fluoro)U-Am-(2'-deoxy-2 (WHO, USAN)

Foreign Names

• Pegaptanibum (Latin)
• Pegaptanib (German)
• Pégaptanib (French)
• Pegaptanib (Spanish)

Generic Names

• Pegaptanib (OS: BAN)
• Pegabtanib Octasodium (OS: USAN)
• EYE001 (IS: Eyetech)
• NX1838 (IS: Eyetech)

Brand Names

• Macugen
  Pfizer, Czech Republic; Pfizer, Spain; Pfizer, Slovenia; Eyetech, United States; Pfizer, Belgium; Pfizer, Bulgaria; Pfizer, Canada; Pfizer, Switzerland; Pfizer, Germany; Pfizer, Denmark; Pfizer, Finland; Pfizer, France; Pfizer, United Kingdom; Pfizer, Greece; Pfizer, Hong Kong; Pfizer, Croatia (Hrvatska); Pfizer, Ireland; Pfizer, Italy; Pfizer, Mexico; Pfizer, Netherlands; Pfizer, Philippines; Pfizer, Sweden; Pfizer, Slovakia; Pfizer, Turkey; Pfizer, United States; Pfizer Limited, Austria

International Drug Name Search

Glossary

BAN	British Approved Name
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name

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